As doctors contemplate a future without opiates to treat chronic pain, some are making the case that eliminating their patients’ pain is not only impossible, it’s unnecessary.

Dr. Hodgert – “Everything in medicine and dentistry has trade-offs. The strongest pain relief cocktail, the scientists tell us, is an NSAID like Advil or Aleve, plus a Tylenol. Need some sedation? Add a glass of wine, or a beer.”

https://www.latimes.com/science/sciencenow/la-sci-sn-treatment-of-pain-opiates-20160316-story.html